Changes to the WADA 2005 Prohibited List
December 22, 2004
As you may know, the World Anti-Doping Agency (WADA) recently announced
significant changes for the 2005 List of Prohibited Substances and Prohibited
Methods of Doping.
Below you will find a summary of these significant changes as well as the
link to the WADA website. USATF strongly recommends that you review the new
rules and policies for 2005, as they go into effect January 1, 2005.
Remember that a substance does not have to be listed on the WADA list
for it to be banned as WADA, USADA, USOC, IAAF, and USATF all recognize 'related
substances' as banned as well.
SUMMARY OF SIGNIFICANT INFORMATION FOR 2005
S1. Anabolic Agents
- Nine substances have been added to the list of examples.
- For endogenous steroids, the T/E ratio, which prompts an investigation,
has been changed from 6:1 to 4:1. (Please note that a doping case can be
put forward if laboratory evidence supports the case even at T/E ratios
less than 4:1.)
S2. Hormones and Related Substances
- The following substances are prohibited in men and women: erythropoietin
(EPO), human growth hormone (hGH), insulin-like growth factor (IGF-1),
mechano growth factor (MGFs), gonadotrophins (LH, hCG), insulin and
S3. Beta-2 agonists (Asthma medications)
- All beta-2 agonists are now prohibited in- and
out-of-competition. Please note that this means that athletes who use
beta-2 agonists for asthma and are tested at either an event or
out-of-competition test will be screened for these substances and
therefore must have an approved ATUE on file with USADA and the
- Salbutamol (albuterol, levalbuterol), salmeterol, terbutaline, and
formoterol are permitted by inhalation only and only with a completed
Abbreviated Therapeutic Use Exemption (ATUE).
- A salbutamol (albuterol) concentration greater than 1,000 ng/mL is a
doping violation (in- or out-of-competition and with or without an
Abbreviated TUE) unless the athlete can prove the
concentration is due to therapeutic use by inhalation.
S4. Agents with Anti-Estrogenic Activity
- Substances that were previously prohibited in men are NOW prohibited in
both men and women. A partial list of examples is provided for each
category. New examples added to this category include anastrozole,
letrozole, aminogluthetimide, formestane, testolactone, raloxifene,
S5. Diuretics and other Masking Agents
- Finasteride (Propecia, Proscar) and other 5-alpha reductase inhibitors
have been added as prohibited substances.
- The contraceptive Yasmin is prohibited as a birth control
methodology due to the presence of the diuretic drospirenone (which is a
- A TUE is not valid if an athlete's urine contains a diuretic in
association with threshold or sub-threshold levels of a Prohibited
- Stimulant rules are unchanged and all are prohibited in-competition.
- Fentanyl and its derivatives have been added to the Prohibited List.
- Eleven narcotics are specifically prohibited in-competition.
- Local anesthetics are permitted unless specifically listed.
- Prohibited in-competition in all sports.
- b. Rules apply only in-competition. Glucocorticosteroids are not tested
- c. Systemic administration is prohibited (intramuscular, intravenous,
oral, and rectal administration).
- d. Local injection, intra-articular injection, inhalation, iontophoresis,
eye drops, ear drops, and nasal sprays etc. require the
submission of an acceptable Abbreviated TUE.
- e. Dermal (topical on skin) applications are allowed and do not require
an Abbreviated TUE.
S10. Miscellaneous Comments
- Insulin is prohibited as a Peptide Hormone - athletes must
file a standard TUE.
- Vicks inhaler is still prohibited due to L-methamphetamine.
- The substances included in the 2005 Monitoring List (bupropion,
caffeine, phenylephrine, phenylpropanolamine, pipradrol, pseudoephedrine,
synephrine and the morphine/codeine ratio) are not considered prohibited
Questions should be directed to the USADA Drug Reference Line at
1-800-233-0393 or online.
For the 2005 Prohibited List of Substances and Methods visit the WADA